Endocrine Abstracts

Introduction: Hyponatraemia is commonly encountered in clinical practice in the context of multiple pathology and marked morbidity. A study was conducted to examine the quality of clinical assessment, care offered and frequency of specialist opinion sought in hospital in-patients with severe hyponatraemia (<120 mmol/l).Audit standards included assessment of fluid status, measurement of ‘baseline investigations’ (urinary sodium and paired os...

Introduction: Nephrolithiasis and osteoporosis are more common in people with primary hyperparathyroidism (PHPT), although the clinical factors associated with this risk are not well characterised. Recent evidence has suggested parathyroid hormone concentration, but not calcium, is associated with mortality in PHPT.Methods: Retrospective analysis of all patients presenting to the Edinburgh Centre for Endocrinology & Diabetes wi...

Introduction: The performance of biochemical and imaging investigations in contributing towards successful surgical outcomes is not well characterised in PHPT.Methods: Retrospective analysis of all patients presenting to the Edinburgh Centre for Endocrinology & Diabetes with PHPT between 2006 and 2014 (n = 611). Parathyroid surgery was performed in 44.8%.Results: PTH was greater than 2x ULN in 34...

Introduction: Nephrolithiasis and osteoporosis are more common in people with primary hyperparathyroidism (PHPT), although the clinical factors associated with this risk are not well characterised. Recent evidence has suggested parathyroid hormone concentration, but not calcium, is associated with mortality in PHPT.Methods: Retrospective analysis of all patients presenting to the Edinburgh Centre for Endocrinology & Diabetes wi...

Introduction: The performance of biochemical and imaging investigations in contributing towards successful surgical outcomes is not well characterised in PHPT.Methods: Retrospective analysis of all patients presenting to the Edinburgh Centre for Endocrinology & Diabetes with PHPT between 2006 and 2014 (n = 611). Parathyroid surgery was performed in 44.8%.Results: PTH was greater than 2x ULN in 34...

Introduction: Adrenal masses may be found as incidental features during abdominal imaging investigations, raising questions as to the need to investigate these lesions for endocrine function or malignancy. This audit utilised published articles and consensus papers to compare our current approach with reported practice in other centres.Method: A retrospective review of the case notes of 21 patients referred to the Endocrine service in the Trust from Nove...

Introduction: Glucocorticoids are hormones that are used extensively in medicine for their anti-inflammatory and immunomodulatory effects. New onset diabetes mellitus is a frequent complication and is the result of an activation of glucocorticoid receptors which stimulate hepatic gluconeogenesis, adipose tissue lipolysis and increase the insulin resistance.Case presentation: We present a case of a 49-year-old Ukrainian female who in 2015 started having h...

Background: With advances in radiological technology, the detection of incidentally discovered pituitary abnormalities is increasing, 90% being secondary to pituitary adenomas. Patient morbidity increases when these lesions are large enough to cause hormone insufficiency or visual field defects, highlighting the importance of appropriate management.Aim: To evaluate management of patients with pituitary incidentaloma in accordance with national guidelines...

Objective: The occurrence of cardiovascular disease (CVD) in patients suffering from type 2 diabetes is a widely discussed issue, less so in those with type 1 (T1DM). The purpose of this study was to evaluate the frequency of these complications as well as certain risk factors that they are associated with.Material and methods: We conducted a retrospective observational study by analyzing data from the observation charts of 106 patients evaluated in our ...

Objective: Diabetic foot complications are a main cause for hospital admissions and spending for patients suffering from T1DM or T2DM. The purpose of this study was to identify and compare possible risk factors for patients suffering from such issues.Methods: We conducted a retrospective observational study analyzing data from observation charts of 324 patients, diagnosed with T1DM or T2DM as well as various foot issues, evaluated between January 2015 &#...